Formulation, Evaluation and Antibacterial Effect of Herbal Toothpaste using leaves and flowers Acmella ciliata

Oral hygiene, an integral part of the body’s general well-being, it is practice keeping mouth clean and disease free by using tooth paste, wash etc. Plants have been a great source medical agents for many years even be considered origin modern medicine. Phytochemicals secondary metabolites plants are active ingredients that possess therapeutic properties as medicine or drug purposes curing diseases improving human health. The main objective this study to formulate develop herbal toothpaste from evaluate its antibacterial activity. containing leaves flowers Acmella ciliate, clove, honey guava ingredients. Different types formulations (F1-F3) were formulated Calcium carbonate cleaning polishing agent, Glycerine humectant, Sodium lauryl sulphate, chloride stain remover teeth, Honey. three evaluated various parameters like colour, taste, fragrance, consistency, pH, shape maintenance, threading property, moisture content foaming character. having aqueous extract tested activity against K. pneumoniae, S. aureus, P. aeruginosa pyogenes. result shows bacteria found more sensitive seen zone inhibition. Further studies would benefit uniform method assessment clinical effectiveness plaque gingivitis safety toothpaste. 
 Keywords: Phytochemicals,Acmella ciliate,herbal toothpast,